Wednesday, December 28, 2016

Sunday, December 25, 2016

Wednesday, December 21, 2016

Monday, December 19, 2016

Thursday, December 15, 2016

Wednesday, December 14, 2016

Tuesday, December 13, 2016

Friday, December 9, 2016

Tuesday, December 6, 2016

Sunday, December 4, 2016

Tuesday, November 29, 2016

Wednesday, November 23, 2016

Monday, November 21, 2016

Tuesday, November 8, 2016

Tuesday, November 1, 2016

Highlighted Article: Dis-organizing Centrosomal Clusters: Specific Cancer Therapy for a Generic Spread?

  11:34 PM   No comments   Edit
Dis-organizing Centrosomal Clusters: Specific Cancer Therapy for a Generic Spread? Author(s): D. Bhakta-Guha, M.E.M. Saeed, H.J. Greten and T. Efferth   Pages 685 - 694 ( 10 ) Abstract: Cancer is a leading cause of mortality and the annual incidence of new cancer cases is rising worldwide. Due to the frequent development of resistance and the side effects of established anti-cancer drugs,...

Sunday, October 23, 2016

Most Cited Article: Daclatasvir: The First of a New Class of Drugs Targeted Against Hepatitis C Virus NS5A

  11:26 PM   No comments   Edit
Daclatasvir: The First of a New Class of Drugs Targeted Against Hepatitis C Virus NS5A Author(s): I. Gentile, F. Borgia, N. Coppola, A.R. Buonomo, G. Castaldo and G. Borgia   Pages 1391-1404 (14) Abstract: Hepatitis C virus (HCV) infection affects about 160 million people worldwide. It is treated with pegylatedinterferon (peg-IFN) and ribavirin, and in the case of patients affected...

Monday, October 17, 2016

Recent Trends in the Discovery of Small Molecule Blockers of Sodium Channels Volume 23, Issue 22

  11:53 PM   No comments   Edit
Article Details Recent Trends in the Discovery of Small Molecule Blockers of Sodium Channels [ Vol. 23 , Issue. 22 ] Author(s): Roberta Gualdani, Maria Maddalena Cavalluzzi and Giovanni LentiniPages 2289-2332 (44) Abstract: Voltage-gated sodium channels (VGSC) are responsible for the selective influx of sodium ions in excitable cells. A number of physiological phenomena such as muscle...

Sunday, October 9, 2016

Tuesday, October 4, 2016

Current Medicinal Chemistry , 23 Issue 21

  10:56 PM   No comments   Edit
Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal...

Current Medicinal Chemistry, 23 Issue 15

  10:55 PM   No comments   Edit
Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal...

Thursday, August 11, 2016

  2:54 AM   No comments   Edit
Mass Production of Pharmaceutically Important Metabolites: Paclitaxel and its Derivatives Journal Name: " Current Medicinal Chemistry."Vol. 20. , No.7, 2013Article: Bioprocessing of Plant In Vitro Systems for the Mass Production of Pharmaceutically Important Metabolites: Paclitaxel and its  ...

Friday, June 24, 2016

Role of Tyrosine Isomers in Acute and Chronic Diseases Leading to Oxidative Stress - A Review

  3:00 AM   No comments   Edit
Author(s): Gergő A. Molnár, Szilárd Kun, Eszter Sélley, Melinda Kertész, Lívia Szélig, Csaba Csontos, Katalin Böddi, Lajos Bogár, Attila Miseta and István WittmannPages 667-685 (19) Abstract: Oxidative stress plays a major role in the pathogenesis of a variety of acute and chronic diseases. Measurement of the oxidative stress-related end products may be performed, e.g. that of structural isomers...

Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson’s Disease

  3:00 AM   No comments   Edit
Author(s): Ikuko Miyazaki and Masato AsanumaPages 686-700 (15) Abstract: Astrocytes are the most abundant neuron-supporting glial cells in the central nervous system. The neuroprotective role of astrocytes has been demonstrated in various neurological disorders such as amyotrophic lateral sclerosis, spinal cord injury, stroke and Parkinson’s disease (PD). Astrocyte dysfunction or loss-of-astrocytes...

Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases

  2:59 AM   No comments   Edit
Author(s): Marisa Cabeza, Araceli Sánchez-Márquez, Mariana Garrido, Aylín Silva and Eugene BratoeffPages 792-815 (24) Abstract: This article summarizes the importance of different targets such as 5α-reductase, 17β-HSD, CYP17A, androgen receptor and protein kinase A for the treatment of prostate cancer and benign prostatic hyperplasia. It is a well known fact that dihydrotestosterone (DHT) is associated...

Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults

  2:58 AM   No comments   Edit
Author(s): Mieke De Buck, Mieke Gouwy, Ji Ming Wang, Jacques Van Snick, Ghislain Opdenakker, Sofie Struyf and Jo Van DammePages 1725-1755 (31) Abstract: Serum amyloid A (SAA) is, like C-reactive protein (CRP), an acute phase protein and can be used as a diagnostic, prognostic or therapy follow-up marker for many diseases. Increases in serum levels of SAA are triggered by physical insults to the...
Subscribe to: Posts (Atom)